Endocrine Abstracts

Background: Guidance on pubertal-induction in hypogonadal adult men is sparse. For adolescent boys, in whom delay is usually constitutional, treatment is typically initiated with pulsed low-dose IM testosterone (T); the dose being progressively increased if/when it becomes clear that endogenous gonadotrophin secretion is not being initiated. In teenagers with organic hypogonadism, the aims are to recapitulate the normal tempo of puberty over 2–3 years and optimise linear ...

Case presentation to demonstrate the presentation and treatment of patients with Thyroid Associated Orbitopathy with particular reference to the role of the Endocrine Nurse in their management.Declaration of interest: There is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.Funding: No specific grant from any funding agency in the public, commercial or not-for-profit sector.<...

Permanent hypoparathyroidism is rare after total thyroidectomy. However, our experience is that often patients remain on alfacalcidol and calcium supplements long-term after thyroidectomy.Administration of these drugs can result in complications such as hypercalcaemia, hypercalciuria, nephrocalcinosis and vitamin D toxicity.Case histories will be used to demonstrate that withdrawal of alfacalcidol should be attempted post thyroidec...

Introduction: The aetiology of Graves’ orbitopathy (GO) is complex and includes genetic and environmental influences. Among potentially controllable risk factors smoking ranks highest. There is strong evidence that smoking cessation benefits patients with GO. The success of secondary prevention strategies depends largely on how the intervention is perceived by patients, especially when it involves lifestyle changes.Objectives: To determine patient p...